Identification of tumor necrosis factor-alpha levels around miniscrews during canine distalization / 대한치과교정학회지

OBJECTIVE: The aim of this study was to measure tumor necrosis factor-alpha (TNF-alpha) levels around miniscrews used for anchorage during a 3-month period of canine distalization. METHODS: Sixteen patients (8 boys, 8 girls; mean age, 16.6 +/- 2.4 years) whose upper first premolars were extracted for orthodontic treatment were included in this study. Miniscrews were used as an anchorage unit in canine distalization. Thirty-two (32) miniscrew implants were placed bilaterally in the alveolar bone between the maxillary second premolars and first molars. The treatment, miniscrew, and control groups comprised upper canines, miniscrew implants, and upper first premolars, respectively. Peri-miniscrew implant crevicular fluid and gingival crevicular fluid were obtained before applying force and at 1, 24, and 48 hours, and at 7 and 21 days, and 3 months after applying force. RESULTS: During the 3-month period, the TNF-alpha levels increased significantly at 24 hours only in the treatment group (p < 0.01). In the miniscrew and control groups, there were no statistically significant changes. No significant differences were observed between groups. CONCLUSIONS: Miniscrews can be conveniently used for anchorage in orthodontics.

Oral manifestations of lamellar ichthyosis; a case report

The name ichthyosis is derived from the Greek ikhthus meaning "fish" and refers to the similarity in appearance of the skin to fish scale. The ichthyoses are a heterogeneous group of disorders. There are few studies about the oral manifestations of these disorders. But early reports of ichthyosis in the Indian and Chinese literature date back to several hundred years. Oral manifestations of the 14-year-old female patient with ichthyosis are presented. Physical examination revealed thick, brownish scales covering the entire body surface including all larger body flexures and corneae. She had short and dry hair. There were no nail abnormalities and hearing loss. We consider that this patient represents a new manifestation of lamellar ichthyosis disease, because congenitally teeth missing and cephalometric analysis measurements have not been reported before